(S)-ethyl 4-(tert-butoxycarbonyl)amino-5-methyl-3-oxohexanoate → HCID 118274919, Verbindung
Reaktionsgleichung
[C:1]([O:5][C:6]([NH:8][C@@H:9]([CH:18]([CH3:20])[CH3:19])[C:10](=[O:17])[CH2:11][C:12]([O:14][CH2:15][CH3:16])=[O:13])=[O:7])([CH3:4])([CH3:3])[CH3:2].[C:21]([O:25]C(NC(C1CCOC1)C(O)=O)=O)(C)(C)C>>[CH2:15]([O:14][C:12](=[O:13])[CH2:11][C:10](=[O:17])[CH:9]([NH:8][C:6]([O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[O:7])[CH:18]1[CH2:19][CH2:21][O:25][CH2:20]1)[CH3:16]Komponenten
3
Versuchsvorschrift
Procedure same as that for ethyl(S)-4-((tert-butoxycarbonyl)amino)-5-methyl-3-oxohexanoate, using 2-((tert-butoxycarbonyl)amino)-2-(tetrahydrofuran-3-yl)acetic acid as a starting material. 1H NMR (CD3OD, 400 MHz): δ 4.25-4.13 (m, 3H), 4.00-3.45 (m, 4H), 2.75-2.65 (m, 1H), 2.12-1.98 (m, 1H), 1.77-1.62 (m, 1H), 1.49 (s 9H), 1.30 (t, J=7.2 Hz, 3H).
Quellen und Nachweise
- ORD-Eintrag
- ord-87bd35c23bb64d5cbda6ab5cc79a5e29
- Quelldatensatz
- uspto-grants-2016_02