HCID 53764590, Verbindung → HCID 54677766, Verbindung
Reaktionsgleichung
[O:1]=[C:2]([NH:8][C:9]1[CH2:14][CH2:13][CH2:12][CH2:11][C:10]=1[C:15]([O:17]CC)=O)[CH2:3][C:4]([O:6][CH3:7])=[O:5].O=C(NC1CCCCC=1C(OC)=O)CC(OC)=O>>[OH:17][C:15]1[C:10]2[CH2:11][CH2:12][CH2:13][CH2:14][C:9]=2[NH:8][C:2](=[O:1])[C:3]=1[C:4]([O:6][CH3:7])=[O:5]Komponenten
3
Versuchsvorschrift
Using the general method of Example 1 Part D, a mixture of methyl 3-oxo-3-[(2-ethoxycarbonylcyclohexen-1-yl)amino]propanoate and methyl 3-oxo-3-[(2-methoxycarbonylcyclohexen-1-yl)amino]propanoate (43.2 g, 0.16 mole) was cyclized to provide 35.5 g of methyl 1,2,5,6,7,8-hexahydro-4-hydroxy-2-oxoquinoline-3-carboxylate as an off white solid.
Quellen und Nachweise
- ORD-Eintrag
- ord-affb582053bf40679bc5f4e7496a0207
- Quelldatensatz
- uspto-grants-1997_05
- Patentnummer
- US05627281
Notizen zur Reaktion
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