methyl (1R,3S)-3-aminocyclopentane-1-carboxylate hydrochloride → Ethyl 4-{3-[4-(biphenyl-4-ylmethoxy)phenyl]propoxy}-3-({[(1S,3R)-3-(methoxycarbonyl)cyclopentyl]amino}carbonyl)benzoate
Reaktionsgleichung
[C:1]1([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[CH:6]=[CH:5][C:4]([CH2:7][O:8][C:9]2[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][CH2:17][O:18][C:19]3[CH:27]=[CH:26][C:25]([C:28]([O:30][CH2:31][CH3:32])=[O:29])=[CH:24][C:20]=3[C:21](O)=[O:22])=[CH:11][CH:10]=2)=[CH:3][CH:2]=1.Cl.[NH2:40][C@H:41]1[CH2:45][CH2:44][C@@H:43]([C:46]([O:48][CH3:49])=[O:47])[CH2:42]1>>[C:1]1([C:33]2[CH:34]=[CH:35][CH:36]=[CH:37][CH:38]=2)[CH:2]=[CH:3][C:4]([CH2:7][O:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:15][CH2:16][CH2:17][O:18][C:19]3[CH:27]=[CH:26][C:25]([C:28]([O:30][CH2:31][CH3:32])=[O:29])=[CH:24][C:20]=3[C:21]([NH:40][C@H:41]3[CH2:45][CH2:44][C@@H:43]([C:46]([O:48][CH3:49])=[O:47])[CH2:42]3)=[O:22])=[CH:13][CH:14]=2)=[CH:5][CH:6]=1Komponenten
3
Versuchsvorschrift
Preparation takes place in analogy to Example 5 from 2-{3-[4-(1,1′-biphenyl-4-yl-methoxy)phenyl]propoxy}-5-(ethoxycarbonyl)benzoic acid and methyl (1R,3S)-3-aminocyclopentanecarboxylate hydrochloride.
Aufarbeitung
- customPreparation