Ethylorthoformate → 4-cyclopropyl-7-nitro-4H-1,2,4-benzothiadiazine 1,1-dioxide

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

In a round-bottom flask, a mixture of 2-cyclopropylamino-5-nitrobenzenesulphonamide (5 g), originating from the Step above, and ethyl orthoformate (50 mL) is heated in the open state at 130° C. for 3 hours. The suspension obtained is cooled on an ice bath and the insoluble material is collected by filtration, washed with ether and dried.

Herkunft & Nachweise