2-Amino-5-nitropyridine → 3-Methyl-6-nitroimidazo[1,2-a]pyridine

HRID 1784727Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1784727
Br[CH:2]([CH3:5])[CH:3]=O.[NH2:6][C:7]1[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][N:8]=1>C(OCC)(=O)C>[CH3:5][C:2]1[N:8]2[CH:9]=[C:10]([N+:13]([O-:15])=[O:14])[CH:11]=[CH:12][C:7]2=[N:6][CH:3]=1

Komponenten

4

Edukt 2

HCID 778882-Amino-5-nitropyridineHCID 3506242-Bromopropanal

Produkt 1

HCID 218273463-Methyl-6-nitroimidazo[1,2-a]pyridine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

Operations similar to Production Example 1-(2) were conducted using 2-bromopropionaldehyde and 2-amino-5-nitropyridine. The solid whereupon obtained was suspended in ethyl acetate, and washed with saturated aqueous sodium hydrogencarbonate solution to provide the title compound as yellow solid.

Aufarbeitung

  1. customThe solid whereupon obtained
  2. washwashed with saturated aqueous sodium hydrogencarbonate solution

Quellen und Nachweise

ORD-Eintrag
ord-08e9c128559343a49cfbb57ed99de03f
Quelldatensatz
uspto-grants-2009_03
Patentnummer
US07504412B2

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