4-Fluorophenylboronic acid → 5-(4-Fluorophenyl)pyridine-2-carboxylic acid
Reaktionsgleichung
Br[C:2]1[CH:3]=[CH:4][C:5]([C:8]([OH:10])=[O:9])=[N:6][CH:7]=1.[F:11][C:12]1[CH:17]=[CH:16][C:15](B(O)O)=[CH:14][CH:13]=1>>[F:11][C:12]1[CH:17]=[CH:16][C:15]([C:2]2[CH:3]=[CH:4][C:5]([C:8]([OH:10])=[O:9])=[N:6][CH:7]=2)=[CH:14][CH:13]=1Komponenten
3
Versuchsvorschrift
Operations similar to those of Production Example 14 were conducted using 5-bromo-2-pyridinecarboxylic acid and 4-fluorophenylboronic acid, to provide the title compound as white solid.
Quellen und Nachweise
- ORD-Eintrag
- ord-cb7c899b325548aa861fe8f1f8dc9983
- Quelldatensatz
- uspto-grants-2009_03
- Patentnummer
- US07504412B2
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