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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1786170Erstellt: 25. Oktober 2026

2-Methoxyacetohydrazide → 9-Chloro-2-methoxymethyl-6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one

https://huagongshe.com/reaction/1786170

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-MethoxyacetohydrazideHCID 2759532—
EduktEthyl 4-chloro-2-cyanophenylcarbamateHCID 21779762—
Produkt9-Chloro-2-methoxymethyl-6H-[1,2,4]triazolo[1,5-c]quinazolin-5-oneHCID 13634786988%

Reaktionsschritte

As described for example 1a) (4-chloro-2-cyano-phenyl)-carbamic acid ethyl ester (71.0 g, 316 mmol) using methoxymethyl-carboxylic acid hydrazide instead of cyclopropane-carboxylic acid hydrazide, was converted to the title compound (73.9 g, 88%) which was obtained as a yellow solid. MS: m/e=264.9 [M+H]+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07507729B2
Quelldatensatzuspto-grants-2009_03
ORD IDord-966f88043c0a4b97b0f02e8322057c1f
Quellennotizuspto-grants-2009_03