Methyl iodide → 2,3-Dihydroxy-N,N,N-trimethylpropan-1-aminium iodide

HRID 1786837Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1786837
[CH3:1][N:2]([CH3:8])[CH2:3][CH:4]([OH:7])[CH2:5][OH:6].[CH3:9][I:10]>C(Cl)Cl>[I-:10].[OH:7][CH:4]([CH2:5][OH:6])[CH2:3][N+:2]([CH3:9])([CH3:8])[CH3:1]

Komponenten

4

Edukt 2

HCID 6328Methyl iodideHCID 790783-(Dimethylamino)-1,2-propanediol

Produkt 1

HCID 187059292,3-Dihydroxy-N,N,N-trimethylpropan-1-aminium iodideAusbeute 100 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To 1 mol of 3-(dimethylamino)-1,2-propanediol 20 (1.2 g) dissolved in CH2Cl2 (5 mL), MeI (2 g, 1.5 mol) was added and the mixture stirred at rt for 1 h. The solution was then filtered and the filtrated recristalise in MeOH/Ether and dried in vacuo. (yield 100%). The characterization data were consistent with the proposed structure.

Aufarbeitung

  1. filtrationThe solution was then filtered
  2. dry with materialthe filtrated recristalise in MeOH/Ether and dried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-1cedecc8418f46aa933e6e0e4a7420d3
Quelldatensatz
uspto-grants-2009_03
Patentnummer
US07507859B2

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