HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tetrahydro-4H-pyran-4-ol → Tetrahydro-4H-pyran-4-yl 3-oxobutanoate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tetrahydro-4H-pyran-4-ol | HCID 74956 | — |
| Edukt | 5-Acetyl-2,2-dimethyl-1,3-dioxane-4,6-dione | HCID 2763470 | — |
| Lösungsmittel | Benzene | HCID 241 | — |
| Produkt | Tetrahydro-4H-pyran-4-yl 3-oxobutanoate | HCID 20189394 | — |
Reaktionsschritte
A solution of tetrahydro-4H-pyran-4-ol (1.6 ml, 16.8 mmoles) and 5-acetyl-2,2-dimethyl-1,3-dioxane-4,6-dione (3.0 g, 16.1 mmoles) in dry benzene (50 ml) was heated under reflux for 4 hours. The solvent was removed in vacuo and the residue distilled at 146°-151°/14 mm Hg to afford the title product as a colourless oil, 2.84 g. Nmr (CDCl3)δ5.1 (m,H), 3.5 (s,3H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04686217 |
| Quelldatensatz | uspto-grants-1987_08 |
| ORD ID | ord-cb09f0193b7f4887922c4b589c6703b0 |
| Quellennotiz | uspto-grants-1987_08 |