HCID 13912877, Verbindung → HCID 20189753, Verbindung

HRID 1789081Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1789081
[CH3:1][N:2]([CH3:17])[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([N+:11]([O-])=O)=[CH:6][C:5]=1[O:14][CH3:15]>C(O)C.[C].[Pd]>[CH3:17][N:2]([CH3:1])[C:3](=[O:16])[C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([NH2:11])=[CH:6][C:5]=1[O:14][CH3:15]

Komponenten

4

Edukt 1

HCID 13912877HCID 13912877, Verbindung

Produkt 1

HCID 20189753HCID 20189753, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A suspension of 3.62 g of N,N-dimethyl 5-amino-2-methoxy4-nitrobenzamide and 150 mg of 10 % palladium carbon in 140 ml of ethanol was stirred at 70°-80° C. under a hydrogen atmosphere. After the absorption of hydrogen was completed, the catalyst was removed by filtration, and the filtrate was evaporated to dryness to give crude N,N-dimethyl 4,5-diamino2-methoxybenzamide, which was then dissolved in 30 ml of tetrahydrofuran.

Aufarbeitung

  1. customAfter the absorption of hydrogen
  2. customthe catalyst was removed by filtration
  3. customthe filtrate was evaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-25d717c20516453d9c35a1cb80195294
Quelldatensatz
uspto-grants-1987_08
Patentnummer
US04686292

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