HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Indoline → cis-1-(1-Acetyl-3-ethoxycarbonylpiperidin-4-yl)indoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Indoline | HCID 10328 | — |
| Edukt | Ethyl 1-acetyl-4-oxo-3-piperidinecarboxylate | HCID 12445847 | — |
| Produkt | cis-1-(1-Acetyl-3-ethoxycarbonylpiperidin-4-yl)indoline | HCID 59909605 | 22% |
Reaktionsschritte
Indoline (12.5 g), ethyl 1-acetyl-4-oxo-3-piperidinecarboxylate (22.3 g) and triacetoxylated sodium borohydride (48.7 g) were treated as in Example 1 to give the title compound (7.12 g) as a pale yellow powder (yield: 22%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07071201B2 |
| Quelldatensatz | uspto-grants-2006_07 |
| ORD ID | ord-feb2337b8d0f47378f7cf0a77a12479f |
| Quellennotiz | uspto-grants-2006_07 |