HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,4-Difluorophenethyl bromide → 1-[1-(2,4-Difluorophenethyl)-piperidin-4-yl]-6-chloro-7-azaindoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,4-Difluorophenethyl bromide | HCID 11298989 | — |
| Edukt | 1-(Piperidin-4-yl)-6-chloro-7-azaindoline | HCID 22038287 | — |
| Produkt | 1-[1-(2,4-Difluorophenethyl)-piperidin-4-yl]-6-chloro-7-azaindoline | HCID 22038121 | 7,8% |
Reaktionsschritte
1-(Piperidin-4-yl)-6-chloro-7-azaindoline (0.5 g) and 2,4-difluorophenethyl bromide (0.43 g) were treated as in Example 2 to give the hydrochloride (74 mg) of the title compound as a brown powder (yield: 7.8%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07071201B2 |
| Quelldatensatz | uspto-grants-2006_07 |
| ORD ID | ord-1d981b97ad054fe78432ba569c0c0283 |
| Quellennotiz | uspto-grants-2006_07 |