Acetaldehyde → 4-Trifluoromethyl-6-ethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one

HRID 1795435

Reaktionsgleichung

Reaktionsgleichung von HRID 1795435
[F:1][C:2]([F:22])([F:21])[C:3]1[C:16]2[C:7](=[CH:8][C:9]3[CH2:10][CH2:11][CH2:12][N:13]([CH2:17][CH2:18]C)[C:14]=3[CH:15]=2)[NH:6][C:5](=[O:20])[CH:4]=1.C(=O)C>>[F:22][C:2]([F:1])([F:21])[C:3]1[C:16]2[C:7](=[CH:8][C:9]3[CH2:10][CH2:11][CH2:12][N:13]([CH2:17][CH3:18])[C:14]=3[CH:15]=2)[NH:6][C:5](=[O:20])[CH:4]=1

Komponenten

3

Edukt 2

HCID 177AcetaldehydeHCID 99445154-Trifluoromethyl-6-propyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one

Produkt 1

HCID 98358134-Trifluoromethyl-6-ethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one

Versuchsvorschrift

This compound was prepared in a similar fashion as that described in Example 84 from Compound 192 (Structure 33 of Scheme VI, where R1=H, n=1) and acetaldehyde. 1H NMR (400 MHz, CDCl3) 11.23 (br. s, 1H), 7.07 (s, 1H), 7.00 (s, 1H), 6.82 (s, 1H), 3.39 (q, 2H, J=7.1), 3.31 (t, 2H, J=5.6), 2.88 (t, 2H, J=6.4), 1.98 (m, 2H), 1.18 (t, 3H, J=7.1).

Aufarbeitung

  1. customThis compound was prepared in a similar fashion as

Quellen und Nachweise

ORD-Eintrag
ord-ac4cf5f17d0a4789b0bf64a71f5db38a
Quelldatensatz
uspto-grants-2006_04
Patentnummer
US07026484B2

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