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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1795436Erstellt: 26. Oktober 2026

Cyclopropanecarboxaldehyde → 4-Trifluoromethyl-6-cyclopropylmethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-one

https://huagongshe.com/reaction/1795436

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktCyclopropanecarboxaldehydeHCID 123114—
Edukt4-Trifluoromethyl-6-ethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-oneHCID 9835813—
Produkt4-Trifluoromethyl-6-cyclopropylmethyl-6,7,8,9-tetrahydropyrido[2,3-g]quinolin-2(1H)-oneHCID 9945017—

Reaktionsschritte

This compound was prepared in a similar fashion as that described in Example 84 from Compound 192 (Structure 33 of Scheme VI, where R1=H, n=1) and cyclopropanecarboxaldehyde. 1H NMR (400 MHz, CDCl3) 11.44 (br. s, 1H), 7.06 (s, 1H), 7.00 (s, 1H), 6.92 (s, 1H), 3.40 (t, 2H, J=5.6), 3.21 (d, 2H, J=6.2), 2.90 (t, 2H, J=6.3), 1.99 (m, 2H), 1.07 (m, 1H), 0.58 (m, 2H), 0.27 (m, 2H).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07026484B2
Quelldatensatzuspto-grants-2006_04
ORD IDord-2ea4c3b5426141eb9a3be087e9a7a5fe
Quellennotizuspto-grants-2006_04