Picolyl chloride hydrochloride → 7-nitro-2-(pyridin-2-yl)methyl-2H-phthalazin-1-one

HRID 1796775

Reaktionsgleichung

Reaktionsgleichung von HRID 1796775
[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH:8]=[N:9][NH:10][C:11]2=[O:14])=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.Cl[CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=1>>[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([CH:8]=[N:9][N:10]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=3)[C:11]2=[O:14])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Komponenten

3

Edukt 2

HCID 23392Picolyl chloride hydrochlorideHCID 2777297-Nitrophthalazin-1(2h)-one

Produkt 1

HCID 221802527-nitro-2-(pyridin-2-yl)methyl-2H-phthalazin-1-one

Versuchsvorschrift

Step (b) of Example 125 was repeated, except that the compound prepared in step (b) of Example 137 and 2-(chloromethyl)pyridine hydrochloride were used as the starting compounds. Thus, 7-nitro-2-(pyridin-2-yl)methyl-2H-phthalazin-1-one was obtained.

Quellen und Nachweise

ORD-Eintrag
ord-612e6398bac4439ca472e51fd9f2ebf2
Quelldatensatz
uspto-grants-2006_04
Patentnummer
US07030120B2

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