Piperidine → 1-[[1-(2-Chloro-ethyl)-1H-pyrrol-2-yl]-(4-fluoro-phenyl)-methyl]-piperidine
Reaktionsgleichung
[N:1]1([CH2:6][CH2:7][Cl:8])[CH:5]=[CH:4][CH:3]=[CH:2]1.[Cl-].[F:10][C:11]1[CH:23]=[CH:22][C:14]([CH:15]=[N+:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)=[CH:13][CH:12]=1.FC1C=CC(C=O)=CC=1.N1CCCCC1>>[Cl:8][CH2:7][CH2:6][N:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:15]([C:14]1[CH:13]=[CH:12][C:11]([F:10])=[CH:23][CH:22]=1)[N:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1Komponenten
5
Versuchsvorschrift
The preparation was carried out in accordance with general synthesis instructions 4 from 2-pyrrol-1-yl-chloroethane and 1-(4-fluoro-benzylidene)-piperidinium chloride, which had been prepared in accordance with example 3 from 4-fluorobenzaldehyde and piperidine.