1-pentylpiperazine → HCID 57496157, Verbindung

HRID 1797971Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1797971
[C:1]([C:3]1[CH:4]=[C:5]([NH:9][C:10](=[O:33])[NH:11][C:12]2[CH:17]=[CH:16][C:15]([S:18]([NH:21][CH2:22][C:23]3[CH:28]=[CH:27][C:26]([S:29](=[O:32])(=[O:31])[NH2:30])=[CH:25][CH:24]=3)(=[O:20])=[O:19])=[CH:14][CH:13]=2)[CH:6]=[CH:7][CH:8]=1)#[N:2].[CH2:34]([N:39]1[CH2:44][CH2:43][NH:42][CH2:41][CH2:40]1)[CH2:35][CH2:36][CH2:37][CH3:38]>>[NH:2]=[C:1]([N:42]1[CH2:43][CH2:44][N:39]([CH2:34][CH2:35][CH2:36][CH2:37][CH3:38])[CH2:40][CH2:41]1)[C:3]1[CH:4]=[C:5]([NH:9][C:10](=[O:33])[NH:11][C:12]2[CH:17]=[CH:16][C:15]([S:18]([NH:21][CH2:22][C:23]3[CH:28]=[CH:27][C:26]([S:29](=[O:32])(=[O:31])[NH2:30])=[CH:25][CH:24]=3)(=[O:20])=[O:19])=[CH:14][CH:13]=2)[CH:6]=[CH:7][CH:8]=1

Komponenten

3

Edukt 2

HCID 27371121-pentylpiperazineHCID 574961804-(3-(3-cyanophenyl)ureido)-N-(4-sulfamoylbenzyl)benzenesulfonamide

Produkt 1

HCID 57496157HCID 57496157, VerbindungAusbeute 13 %

Versuchsvorschrift

The title compound was prepared from 4-(3-(3-cyanophenyl)ureido)-N-(4-sulfamoylbenzyl)benzenesulfonamide following procedure C and using 2 equivalents of n-pentylpiperazine as secondary amine. The product was purified by preparative HPLC.

Aufarbeitung

  1. customThe product was purified by preparative HPLC

Quellen und Nachweise

ORD-Eintrag
ord-39db7789c0b447879f89c0d31938bd79
Quelldatensatz
uspto-grants-2013_01
Patentnummer
US08343963B2

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