Methyl (2E)-3-{3-fluoro-2-[(triphenylphosphoranylidene)amino]phenyl}propenoate → HCID 58941058, Verbindung
Reaktionsgleichung
[F:1][C:2]1[C:3]([N:14]=P(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=[C:4](/[CH:8]=[CH:9]/[C:10]([O:12][CH3:13])=[O:11])[CH:5]=[CH:6][CH:7]=1.[N:34]([C:37]1[CH:42]=[C:41]([C:43]([F:46])([F:45])[F:44])[CH:40]=[CH:39][C:38]=1[O:47][CH3:48])=[C:35]=O.[F:49][C:50]1[CH:58]=[CH:57][C:56]2[N:55]3[CH2:59][CH2:60][NH:61][CH2:62][C:54]3=[CH:53][C:52]=2[CH:51]=1>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]2[C:3]=1[N:14]=[C:35]([N:61]1[CH2:60][CH2:59][N:55]3[C:56]4[CH:57]=[CH:58][C:50]([F:49])=[CH:51][C:52]=4[CH:53]=[C:54]3[CH2:62]1)[N:34]([C:37]1[CH:42]=[C:41]([C:43]([F:46])([F:45])[F:44])[CH:40]=[CH:39][C:38]=1[O:47][CH3:48])[CH:8]2[CH2:9][C:10]([O:12][CH3:13])=[O:11]Komponenten
4
Versuchsvorschrift
Starting with 182 mg (0.4 mmol) of the irninophosphorane from Example 12A, 86 mg of 2-isocyanato-1-methoxy-4-(trifluoromethyl)benzene and 130 mg (0.4 mmol) of 8-fluoro-1,2,3,4-tetrahydropyrazino[1,2-a]indole from Example 36A, the general procedure [M] gives 95 mg (35% of theory) of product.