Hydrochloric Acid → Trans-4-(2-amino-cyclopentyl)-N-(5-isopropyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide hydrochloride
Reaktionsgleichung
[CH:1]([C:4]1[S:8][C:7]([NH:9][S:10]([C:13]2[CH:18]=[CH:17][C:16]([C@@H:19]3[CH2:23][CH2:22][CH2:21][C@H:20]3[NH:24]C(=O)C)=[CH:15][CH:14]=2)(=[O:12])=[O:11])=[N:6][N:5]=1)([CH3:3])[CH3:2].[ClH:28]>>[ClH:28].[NH2:24][C@@H:20]1[CH2:21][CH2:22][CH2:23][C@H:19]1[C:16]1[CH:17]=[CH:18][C:13]([S:10]([NH:9][C:7]2[S:8][C:4]([CH:1]([CH3:3])[CH3:2])=[N:5][N:6]=2)(=[O:12])=[O:11])=[CH:14][CH:15]=1Komponenten
3
Versuchsvorschrift
Was prepared from 150 mg trans-N-{2-[4-(5-isopropyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-phenyl]-cyclopentyl}-acetamide by heating it in 10 ml of 2n HCl at 100° C. for 13 hours.
Quellen und Nachweise
- ORD-Eintrag
- ord-e144bedc39e844d7a3c7bb2e77e4c609
- Quelldatensatz
- uspto-grants-2013_01