Thionyl Chloride → 2-(Chloromethyl)-4H-1-benzopyran-4-one

HRID 1801698Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1801698
O[CH2:2][C:3]1[O:4][C:5]2[C:10]([C:11](=[O:13])[CH:12]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.S(Cl)([Cl:16])=O>C(Cl)(Cl)Cl>[Cl:16][CH2:2][C:3]1[O:4][C:5]2[C:10]([C:11](=[O:13])[CH:12]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2

Komponenten

4

Edukt 2

HCID 24386Thionyl ChlorideHCID 12536095HCID 12536095, Verbindung

Produkt 1

HCID 140019552-(Chloromethyl)-4H-1-benzopyran-4-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

The 2-(hydroxymethyl)-4H-chromen-4-one was dissolved in 30 ml of anhydrous chloroform at room temperature, 1 ml of thionyl chloride was added to the solution, and reaction mixture was stirred at room temperature for 24 hours. The solvent was thereafter evaporated, and the obtained liquid was dissolved in anhydrous hexane, which was also evaporated again to give 2-(chloromethyl)-4H-chromen-4-one which was further reacted without purification.

Aufarbeitung

  1. customThe solvent was thereafter evaporated
  2. dissolutionthe obtained liquid was dissolved in anhydrous hexane
  3. customwhich was also evaporated again

Quellen und Nachweise

ORD-Eintrag
ord-b5905400d7834c8f8da2c7f4396fe488
Quelldatensatz
uspto-grants-2013_01
Patentnummer
US08349850B2

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