Methanol → trans-4-(5'-Chloro-6-fluoro-2,4'-bipyridin-2'-yl-amino)cyclohexanol
Reaktionsgleichung
[CH3:33][O:34][CH2:35][CH2:36][O:37][CH3:38].[CH3:45][OH:46].[CH3:47][CH2:48][O:49][C:50](=[O:51])[CH3:52].[Cl:1][c:2]1[c:3]([I:16])[cH:4][c:5]([NH:8][CH:9]2[CH2:10][CH2:11][CH:12]([OH:15])[CH2:13][CH2:14]2)[n:6][cH:7]1.[F:17][c:18]1[n:19][c:20]([B:24]2[O:25][C:26]([CH3:27])([CH3:28])[C:29]([CH3:30])([CH3:31])[O:32]2)[cH:21][cH:22][cH:23]1.[Na+:39].[Na+:40].[O-:41][C:42](=[O:43])[O-:44]>>[Cl:1][c:2]1[c:3](-[c:20]2[n:19][c:18]([F:17])[cH:23][cH:22][cH:21]2)[cH:4][c:5]([NH:8][CH:9]2[CH2:10][CH2:11][CH:12]([OH:15])[CH2:13][CH2:14]2)[n:6][cH:7]1
