Triethylamine → HCID 54192011, Verbindung

HRID 1803060Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1803060
[NH2:1][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.[CH2:9](N(CC)CC)[CH3:10]>C1COCC1>[CH:2]1[N:1]=[CH:10][CH2:9][N:4]2[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=12

Komponenten

4

Edukt 2

HCID 8471TriethylamineHCID 195092-Pyridinemethanamine

Produkt 1

HCID 54192011HCID 54192011, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

2-aminomethyl pyridine (10 mmol) was dissolved together with triethylamine (20 mmol) in THF (50 ml) and a solution of the corresponding bis-imidoylchloride (10 mmol) was added dropwise. Then the solution was refluxed for ca. 4 h and after cooling-down the solvent was removed under reduced pressure. The residue was washed with little cold methanol and subsequently, the residue was recrystallized from acetonitrile or THF.

Aufarbeitung

  1. temperatureThen the solution was refluxed for ca. 4 h
  2. temperatureafter cooling-down the solvent
  3. customwas removed under reduced pressure
  4. washThe residue was washed with little cold methanol
  5. customsubsequently, the residue was recrystallized from acetonitrile or THF

Quellen und Nachweise

ORD-Eintrag
ord-78cd227edabb4a47b9ff21c79ea7bae2
Quelldatensatz
uspto-grants-2013_01
Patentnummer
US08350038B2

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