HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Bromo-2-fluorobenzoyl chloride → (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyrazin-2-yl)piperazin-1-yl]methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Bromo-2-fluorobenzoyl chloride | HCID 2734026 | — |
| Edukt | (3,5-Dimethylpyrazin-2-yl)piperazine hydrochloride | HCID 67381341 | — |
| Produkt | (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyrazin-2-yl)piperazin-1-yl]methanone | HCID 58484696 | 69,9% |
Reaktionsschritte
By reaction and treatment in the same manner as in Preparation Example 8 and using 4-bromo-2-fluorobenzoyl chloride (1.1 g) and 1-(3,5-dimethylpyrazin-2-yl)piperazine hydrochloride (915 mg) described in Preparation Example 59, the title compound (1.1 g) was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08354401B2 |
| Quelldatensatz | uspto-grants-2013_01 |
| ORD ID | ord-4cd6e7e1f65a44afb88ec664acedf589 |
| Quellennotiz | uspto-grants-2013_01 |