2-Oxazolidinone → 3-{3-(3-Acetyl-2-oxoimidazolidin-1-yl)-4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-Oxazolidinone	HCID 73949	—
Edukt	1-Acetyl-3-{5-chloro-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}imidazolidin-2-one	HCID 58484683	—
Produkt	3-{3-(3-Acetyl-2-oxoimidazolidin-1-yl)-4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}oxazolidin-2-one	HCID 67380912	10,2%

Reaktionsschritte

By reaction and treatment in the same manner as in Example 201 and using 1-acetyl-3-{5-chloro-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}imidazolidin-2-one (221.5 mg) described in Preparation Example 126 and oxazolidin-2-one (42.3 mg), the title compound (25.2 mg) was obtained.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08354401B2
Quelldatensatz	uspto-grants-2013_01
ORD ID	ord-81aa1012ec014325a0bf93502b787b04
Quellennotiz	uspto-grants-2013_01