5,5-Dimethyloxazolin-2-one → 3-{3-(3-Acetyl-2-oxoimidazolidin-1-yl)-4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}-5,5-dimethyloxazolidin-2-one

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	5,5-Dimethyloxazolin-2-one	HCID 21464782	—
Edukt	1-Acetyl-3-{5-chloro-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}imidazolidin-2-one	HCID 58484683	—
Produkt	3-{3-(3-Acetyl-2-oxoimidazolidin-1-yl)-4-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}-5,5-dimethyloxazolidin-2-one	HCID 58484611	11,3%

Reaktionsschritte

By reaction and treatment in the same manner as in Example 201 and using 1-acetyl-3-{5-chloro-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}imidazolidin-2-one (653 mg) described in Preparation Example 126 and 5,5-dimethyloxazolin-2-one (165 mg) described in Preparation Example 43, the title compound (86.5 mg) was obtained.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08354401B2
Quelldatensatz	uspto-grants-2013_01
ORD ID	ord-f5f36e47716a4a65bbcfb41ab8c4e73f
Quellennotiz	uspto-grants-2013_01