L-Tyrosine 1,1-dimethylethyl ester → HCID 178467516, Verbindung

HRID 18052

Reaktionsgleichung

Reaktionsgleichung von HRID 18052
C(O[C:4]1[C:8]([O:9][CH2:10][CH3:11])=[N:7][S:6](=[O:13])(=[O:12])[N:5]=1)C.[C:14]([O:18][C:19](=[O:30])[C@H:20]([CH2:22][C:23]1[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=1)[NH2:21])([CH3:17])([CH3:16])[CH3:15]>C(O)C>[C:14]([O:18][C:19](=[O:30])[C@H:20]([CH2:22][C:23]1[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=1)[NH:21][C:4]1[C:8]([O:9][CH2:10][CH3:11])=[N:7][S:6](=[O:12])(=[O:13])[N:5]=1)([CH3:17])([CH3:15])[CH3:16]

Komponenten

4

Edukt 2

HCID 6950582L-Tyrosine 1,1-dimethylethyl esterHCID 112179953,4-Diethoxy-1,2,5-thiadiazole-1,1-dioxide

Produkt 1

HCID 178467516HCID 178467516, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 3,4-diethyloxy-1,1-dioxo-1,2,5-thiadiazole (400 mg, 1.94 mmol)and L-tyrosine t-butyl ester (1.25 g, 5.2 mmol) in ethanol (25 mL) was stirred at room temperature overnight. Solvent was removed under reduced pressure and the product used in further transformations without further purification (Yield 790 mg).

Aufarbeitung

  1. customSolvent was removed under reduced pressure
  2. customthe product used in further transformations without further purification (Yield 790 mg)

Quellen und Nachweise

ORD-Eintrag
ord-699410693ba64de790256f5ae2554dde
Quelldatensatz
uspto-grants-2010_06
Patentnummer
US07741328B2

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