Dimethylformamide → 4-(4-Fluoro-2-methylindol-5-yl)oxy-6-methoxy-7-(3-(4-methylsulfonylpiperazin-1-yl)propoxy)cinnoline
Reaktionsgleichung
[CH2:76]([Cl:77])[Cl:78].[CH3:57][S:58](=[O:59])(=[O:60])[N:61]1[CH2:62][CH2:63][N:64]([CH2:67][CH2:68][CH2:69][OH:70])[CH2:65][CH2:66]1.[F:13][c:14]1[c:15]2[cH:16][c:17]([CH3:37])[nH:18][c:19]2[cH:20][cH:21][c:22]1[O:23][c:24]1[cH:25][n:26][n:27][c:28]2[cH:29][c:30]([OH:36])[c:31]([O:34][CH3:35])[cH:32][c:33]12.[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[O:71]=[CH:72][N:73]([CH3:74])[CH3:75].[c:38]1([P:39]([c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[c:46]2[cH:47][cH:48][cH:49][cH:50][cH:51]2)[cH:52][cH:53][cH:54][cH:55][cH:56]1>>[F:13][c:14]1[c:15]2[cH:16][c:17]([CH3:37])[nH:18][c:19]2[cH:20][cH:21][c:22]1[O:23][c:24]1[cH:25][n:26][n:27][c:28]2[cH:29][c:30]([O:36][CH2:69][CH2:68][CH2:67][N:64]3[CH2:63][CH2:62][N:61]([S:58]([CH3:57])(=[O:59])=[O:60])[CH2:66][CH2:65]3)[c:31]([O:34][CH3:35])[cH:32][c:33]12
