HCID 86641156, Verbindung → HCID 86649536, Verbindung

HRID 1807693Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1807693
C(C1N=[CH:13][C:12]2[CH2:11][CH2:10][C:9]3[N:15]=[C:16]([NH:18][C:19]([N:21]4[CH:25]=[CH:24][N:23]=[CH:22]4)=[O:20])[S:17][C:8]=3[C:7]=2N=1)(C)(C)C.Cl.[F:27][C:28]([F:36])([F:35])[C:29]([CH3:34])([CH3:33])[C:30]([NH2:32])=[NH:31]>>[F:27][C:28]([F:36])([F:35])[C:29]([C:30]1[N:32]=[CH:13][C:12]2[CH2:11][CH2:10][C:9]3[N:15]=[C:16]([NH:18][C:19]([N:21]4[CH:25]=[CH:24][N:23]=[CH:22]4)=[O:20])[S:17][C:8]=3[C:7]=2[N:31]=1)([CH3:34])[CH3:33]

Komponenten

3

Edukt 2

HCID 86641156HCID 86641156, VerbindungHCID 86649527Imidazole-1-carboxylic acid (8-tert-butyl-4,5-dihydro-thiazolo[4,5-h]quinazolin-2-yl)-amide

Produkt 1

HCID 86649536HCID 86649536, Verbindung

Versuchsvorschrift

The title compound was prepared in analogy to the procedure described for Intermediate A but in Stage A.3 3,3,3-trifluoro-2,2-dimethyl-propionamidine hydrochloride (Stage 44.2) was used instead of tert-butylamidine hydrochloride.

Quellen und Nachweise

ORD-Eintrag
ord-ef4d0afb43fd47e68948d783452f8363
Quelldatensatz
uspto-grants-2013_01
Patentnummer
US08357707B2

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