Cyclopropanecarbonyl chloride → {2'-[(Cyclopropanecarbonyl-ethyl-amino)-methyl]-6-methoxy-5'-methyl-biphenyl-3-yl}-acetic acid ethyl ester

HRID 1810500

Reaktionsgleichung

Reaktionsgleichung von HRID 1810500
[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[C:18]([CH3:20])[CH:17]=[CH:16][C:15]=2[CH2:21][NH:22][CH2:23][CH3:24])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2].[CH:26]1([C:29](Cl)=[O:30])[CH2:28][CH2:27]1>>[CH2:1]([O:3][C:4](=[O:25])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[C:18]([CH3:20])[CH:17]=[CH:16][C:15]=2[CH2:21][N:22]([C:29]([CH:26]2[CH2:28][CH2:27]2)=[O:30])[CH2:23][CH3:24])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2]

Komponenten

3

Edukt 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 58149093(2'-Ethylaminomethyl-6-methoxy-5'-methyl-biphenyl-3-yl)-acetic acid ethyl ester

Produkt 1

HCID 58149183{2'-[(Cyclopropanecarbonyl-ethyl-amino)-methyl]-6-methoxy-5'-methyl-biphenyl-3-yl}-acetic acid ethyl ester

Versuchsvorschrift

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-ethylaminomethyl-6-methoxy-5′-methyl-biphenyl-3-yl)-acetic acid ethyl ester and cyclopropanecarbonyl chloride.

Aufarbeitung

  1. customPrepared

Quellen und Nachweise

ORD-Eintrag
ord-09a9d46449f646549c4d1ebc8cf6531e
Quelldatensatz
uspto-grants-2013_01
Patentnummer
US08362044B2

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