Ethanol → (5-Benzyloxy-2-chloro-phenyl)-acetic acid ethyl ester

HRID 1810530Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1810530
[CH2:1]([O:8][C:9]1[CH:10]=[CH:11][C:12]([Cl:19])=[C:13]([CH2:15][C:16]([OH:18])=[O:17])[CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(=O)(=O)(O)O.[CH3:25][CH2:26]O>>[CH2:25]([O:17][C:16](=[O:18])[CH2:15][C:13]1[CH:14]=[C:9]([O:8][CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH:10]=[CH:11][C:12]=1[Cl:19])[CH3:26]

Komponenten

4

Edukt 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 58149280(5-Benzyloxy-2-chloro-phenyl)-acetic acid

Produkt 1

HCID 58148945(5-Benzyloxy-2-chloro-phenyl)-acetic acid ethyl ester

Versuchsvorschrift

To (5-benzyloxy-2-chloro-phenyl)-acetic acid (1.5 g, 5.4 mmol) in EtOH (30 mL) was added sulfuric acid (1 mL), and the mixture was stirred overnight at room temperature. Once no starting material was seen by analytical LCMS, the reaction was worked up to give the title compound.

Quellen und Nachweise

ORD-Eintrag
ord-f33bcd6ccba748dcad9a96cec4bda8f5
Quelldatensatz
uspto-grants-2013_01
Patentnummer
US08362044B2

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