Bromoform → 4-Bromo-2-[[(2,3-difluorophenyl)methyl]thio]-7,8-dihydro-7-oxo-6-pteridinecarboxylic Acid Ethyl Ester
Reaktionsgleichung
[CH2:1]([O:3][C:4]([C:6]1[C:15](=[O:16])[NH:14][C:13]2[N:12]=[C:11]([S:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([F:25])[C:20]=3[F:26])[N:10]=[C:9](N)[C:8]=2[N:7]=1)=[O:5])[CH3:2].C(Br)(Br)[Br:29]>>[CH2:1]([O:3][C:4]([C:6]1[C:15](=[O:16])[NH:14][C:13]2[N:12]=[C:11]([S:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([F:25])[C:20]=3[F:26])[N:10]=[C:9]([Br:29])[C:8]=2[N:7]=1)=[O:5])[CH3:2]Komponenten
3
Versuchsvorschrift
The sub-titled compound was prepared from the product of example 36, step (a) (2 g) and bromoform (40 ml) using the method of Example 3, step (b).
Quellen und Nachweise
- ORD-Eintrag
- ord-5bcabe344bff41fb992881026bd9a1b9
- Quelldatensatz
- uspto-grants-2005_04