Isatoic Anhydride → HCID 22493286, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([N:6]([CH:8]([CH3:10])[CH3:9])[CH3:7])=[O:5].[CH3:15][NH:16][CH:17]([CH3:19])C.C12C(=CC=CC=1)[NH:25][C:24](=O)OC2=O>>[NH:16]1[CH2:15][CH2:24][N:25]=[C:17]1[CH2:19][NH:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([N:6]([CH:8]([CH3:10])[CH3:9])[CH3:7])=[O:5]Komponenten
4
Versuchsvorschrift
2-Amino-N-isopropyl-N-methylbenzamide (prepared from N-methylisopropylamine and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino]-N-isopropyl-N-methylbenzamide.
Aufarbeitung
- customwere reacted