1-Amino-2-propanol → HCID 22493328, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([NH:6][CH2:7][CH:8]([OH:10])[CH3:9])=[O:5].[NH2:15][CH2:16][CH:17](O)C.[C:20]12[C:26](=CC=CC=1)[NH:25]C(=O)OC2=O>>[NH:15]1[CH2:16][CH2:17][N:25]=[C:26]1[CH2:20][NH:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[C:4]([NH:6][CH2:7][CH:8]([OH:10])[CH3:9])=[O:5]Komponenten
4
Versuchsvorschrift
2-Amino-N-(2-hydroxypropyl)benzamide (prepared from 1-amino-2-propanol and isatoic anhydride, using the methods described in Example 17) and CMI were reacted using conditions described in the general procedure for CMI coupling to give 2-[(4,5-dihydro-1H-imidazol-2-ylmethyl)amino)-N-(2-hydroxypropyl)benzamide, isolated as the hydrochloride salt.
Aufarbeitung
- customwere reacted