2-Nitrobenzamide → N-[(dimethylamino)ethylidene]-2-nitrobenzamide

HRID 1816299Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1816299
[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6]([NH2:8])=[O:7])([O-:3])=[O:2].CO[C:15](OC)([N:17]([CH3:19])[CH3:18])[CH3:16]>>[CH3:18][N:17]([CH2:15][CH:16]=[N:8][C:6](=[O:7])[C:5]1[CH:9]=[CH:10][CH:11]=[CH:12][C:4]=1[N+:1]([O-:3])=[O:2])[CH3:19]

Komponenten

3

Edukt 2

HCID 118762-NitrobenzamideHCID 878351,1-Dimethoxyethyl(dimethyl)amine

Produkt 1

HCID 57019786N-[(dimethylamino)ethylidene]-2-nitrobenzamide

Reaktionsbedingungen

Temperatur
120 °C

Versuchsvorschrift

2-Nitrobenzamide (12.4 g, 75 mmol) was dissolved to dimethylacetamide-dimethylacetal (25 mL ) and heated to 120° C. for 2 hours. Upon cooling, the reaction was passed through a short silica column, eluting with ethyl acetate. The crystals that formed in the collected eluent were collected by filtration and rinsed with diethyl ether to provide N-[(dimethylamino)ethylidene]-2-nitrobenzamide (7.73 g).

Aufarbeitung

  1. temperatureUpon cooling
  2. washeluting with ethyl acetate
  3. customThe crystals that formed in the collected eluent
  4. filtrationwere collected by filtration
  5. washrinsed with diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-aa53b9ca7e0b408fa77a16147ab5a853
Quelldatensatz
uspto-grants-2005_04
Patentnummer
US06884801B1

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