Reaktionsgleichung
[NH2:1][CH2:2][C:3]1[CH:4]=[C:5]([CH2:11][CH:12]([O:18][CH:19]([CH3:21])[CH3:20])[C:13]([O:15]CC)=[O:14])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[CH3:22][O:23][C:24]1[CH:32]=[C:31]([C:33]([F:36])([F:35])[F:34])[CH:30]=[CH:29][C:25]=1[C:26](O)=[O:27]>>[CH:19]([O:18][CH:12]([CH2:11][C:5]1[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([CH2:2][NH:1][C:26](=[O:27])[C:25]2[CH:29]=[CH:30][C:31]([C:33]([F:35])([F:36])[F:34])=[CH:32][C:24]=2[O:23][CH3:22])[CH:4]=1)[C:13]([OH:15])=[O:14])([CH3:20])[CH3:21]Komponenten
3
Versuchsvorschrift
0.15 g of ethyl 3-[3-(aminomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate and 0.24 g of 2-methoxy-4-(trifluoromethyl)benzoic acid were treated in the same manners as in Example 19d) and then in Example 1d), to give 0.15 g of 2-isopropoxy-3-[4-methoxy-3-({[2-methoxy-4-(trifluoromethyl)benzoyl]amino}methyl)phenyl]propanoic acid as a pale yellow oil.
Quellen und Nachweise
- ORD-Eintrag
- ord-4e7a67575b6047ea9866f6d2800447bc
- Quelldatensatz
- uspto-grants-2005_04
- Patentnummer
- US06884821B1
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