Cyclopropanecarboxylic acid → HCID 10256103, Verbindung
Reaktionsgleichung
[CH3:1][C:2]([CH3:30])([CH3:29])[C:3](=[O:28])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]([C:17]2[S:21][C:20]([S:22]([NH2:25])(=[O:24])=[O:23])=[C:19]([CH3:26])[CH:18]=2)([CH2:15][CH3:16])[CH2:13][CH3:14])=[CH:8][C:7]=1[CH3:27].[CH:31]1([C:34](O)=[O:35])[CH2:33][CH2:32]1>>[CH:31]1([C:34]([NH:25][S:22]([C:20]2[S:21][C:17]([C:12]([C:9]3[CH:10]=[CH:11][C:6]([O:5][CH2:4][C:3](=[O:28])[C:2]([CH3:1])([CH3:29])[CH3:30])=[C:7]([CH3:27])[CH:8]=3)([CH2:13][CH3:14])[CH2:15][CH3:16])=[CH:18][C:19]=2[CH3:26])(=[O:24])=[O:23])=[O:35])[CH2:33][CH2:32]1Komponenten
3
Versuchsvorschrift
Using a procedure analogous to Example 163, 5-{1-[4-(3,3-dimethyl-2-oxo-butoxy)-3-methyl-phenyl]-1-ethyl-propyl}-3-methyl-thiophene-2-sulfonic acid amide and cyclopropanecarboxylic acid give the title compound (60%).
Quellen und Nachweise
- ORD-Eintrag
- ord-722c35c1cd55441488580c0dbb8ee5e1
- Quelldatensatz
- uspto-grants-2009_10