Ethyl Acetate → N-(2,4-dichloro-3-{2-[3-(1-hydroxy-ethyl)-phenylamino]-8-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-6-yl}-phenyl)-3-trifluoromethyl-benzamide

HRID 182023

Reaktionsgleichung

Reaktionsgleichung von HRID 182023
[CH3:48][CH2:49][O:50][C:51]([CH3:52])=[O:53].[Cl:1][c:2]1[c:3]([NH:25][C:26]([c:27]2[cH:28][c:29]([C:33]([F:34])([F:35])[F:36])[cH:30][cH:31][cH:32]2)=[O:37])[cH:4][cH:5][c:6]([Cl:24])[c:7]1-[c:8]1[cH:9][c:10]2[c:11]([n:12][c:13]([S:16]([CH3:17])(=[O:18])=[O:19])[n:14][cH:15]2)[n:20]([CH3:23])[c:21]1=[O:22].[OH:38][CH:39]([CH3:40])[c:41]1[cH:42][c:43]([NH2:44])[cH:45][cH:46][cH:47]1>>[Cl:1][c:2]1[c:3]([NH:25][C:26]([c:27]2[cH:28][c:29]([C:33]([F:34])([F:35])[F:36])[cH:30][cH:31][cH:32]2)=[O:37])[cH:4][cH:5][c:6]([Cl:24])[c:7]1-[c:8]1[cH:9][c:10]2[c:11]([n:12][c:13]([NH:44][c:43]3[cH:42][c:41]([CH:39]([OH:38])[CH3:40])[cH:47][cH:46][cH:45]3)[n:14][cH:15]2)[n:20]([CH3:23])[c:21]1=[O:22]

Komponenten

4

Edukt 3

HCID 8857Ethyl AcetateHCID 2224611-(3-Aminophenyl)ethanolHCID 59833791N-[2,4-dichloro-3-(2-methanesulfonyl-8-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-6-yl)-phenyl]-3-trifluoromethyl-benzamide

Produkt 1

HCID 11273621N-(2,4-dichloro-3-{2-[3-(1-hydroxy-ethyl)-phenylamino]-8-methyl-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-6-yl}-phenyl)-3-trifluoromethyl-benzamide

Quellen und Nachweise

ORD-Eintrag
ord-0a876747e0a04a5a961cd5798b46cec9
Quelldatensatz
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Verknüpfte Notizen

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