HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride → HCID 68682988, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Edukt | 4,4-Difluoropiperidine hydrochloride | HCID 2758351 | — |
| Edukt | 5-(4-tert-butoxycarbonyl-[1,4]diazepane-1-carbonyl)-1-isopropyl-1H-indole-2-carboxylic acid | HCID 68538212 | — |
| Lösungsmittel | Triethylamine | HCID 8471 | — |
| Produkt | HCID 68682988 | HCID 68682988 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example 1, from 5-(4-tert-butoxycarbonyl-[1,4]diazepane-1-carbonyl)-1-isopropyl-1H-indole-2-carboxylic acid, 4,4-difluoropiperidine hydrochloride, triethylamine and 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride, to afford the product as a yellow solid (70%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07601711B2 |
| Quelldatensatz | uspto-grants-2009_10 |
| ORD ID | ord-85a177e75c284709818f9bc577ca36f1 |
| Quellennotiz | uspto-grants-2009_10 |