2-(2-Chloro-4-nitro-phenylsulfanyl)-benzothiazole-5-carbonitrile → 2-(4-Amino2-chlorophenylsulfanyl)-benzothiazole-5-carbonitrile
Reaktionsgleichung
[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[CH:4][C:3]=1[S:11][C:12]1[S:13][C:14]2[CH:20]=[CH:19][C:18]([C:21]#[N:22])=[CH:17][C:15]=2[N:16]=1.O.O.[Sn](Cl)(Cl)(Cl)Cl>>[NH2:8][C:6]1[CH:5]=[CH:4][C:3]([S:11][C:12]2[S:13][C:14]3[CH:20]=[CH:19][C:18]([C:21]#[N:22])=[CH:17][C:15]=3[N:16]=2)=[C:2]([Cl:1])[CH:7]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared using the method of example 270, starting with 2-(2-chloro-4-nitro-phenylsulfanyl)-benzothiazole-5-carbonitrile (263) (1.59 g, 4.58 mmol), tin chloride dihydrate (Aldrich, 5.18 g, 22.9 mmol). Compound 275 (1.35 g, 93%) was obtained as a yellowish solid.
Aufarbeitung
- customThe title compound was prepared