Piperidine → 4-Piperidinylbut-1-ene

HRID 1824513

Reaktionsgleichung

Reaktionsgleichung von HRID 1824513
Br[CH2:2][CH2:3][CH:4]=[CH2:5].[NH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1>>[N:6]1([CH2:7][CH2:8][CH:9]=[CH2:10])[CH2:11][CH2:5][CH2:4][CH2:3][CH2:2]1

Komponenten

3

Edukt 2

HCID 8082PiperidineHCID 21241Homoallyl bromide

Produkt 1

HCID 45622824-Piperidinylbut-1-eneAusbeute 93,4 %

Versuchsvorschrift

4-Bromobut-1-ene (1.35 g) was treated with piperidine (1.7 g) and heated at reflux for 3 hours. The mixture was cooled to ambient temperature, filtered and the residue washed with ether (50 mL). The combined filtrate and washings were evaporated to give the title compound (1.3 g).

Aufarbeitung

  1. temperatureheated
  2. temperatureat reflux for 3 hours
  3. filtrationfiltered
  4. washthe residue washed with ether (50 mL)
  5. customThe combined filtrate and washings were evaporated

Quellen und Nachweise

ORD-Eintrag
ord-adb29397f4884d54a3b13354f001a0f2
Quelldatensatz
uspto-grants-2006_05
Patentnummer
US07041827B2

Verknüpfte Notizen

Wird geladen…