HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-[4-[4-Hydroxybut-1-ynyl]phenyl]-7-methylimidazo[1,2-a]pyridine → 2-[4-[4-Hydroxybutyl]phenyl]-7-methylimidazo[1,2-a]pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-[4-[4-Hydroxybut-1-ynyl]phenyl]-7-methylimidazo[1,2-a]pyridine | HCID 22015594 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 2-[4-[4-Hydroxybutyl]phenyl]-7-methylimidazo[1,2-a]pyridine | HCID 22015655 | 92,6% |
Reaktionsschritte
The product of Step B, Example 33 (0.3 g) in ethanol (15 mL) was hydrogenated over 5% palladium on barium sulfate (0.06 g) for 4.5 hours. The reaction mixture was filtered and evaporated to afford the title compound (0.282 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07041828B2 |
| Quelldatensatz | uspto-grants-2006_05 |
| ORD ID | ord-7dabd75f4f5445a89911f985c724bbc0 |
| Quellennotiz | uspto-grants-2006_05 |