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HRID 1824548Erstellt: 26. Oktober 2026

2-[4-[4-Hydroxybut-1-ynyl]phenyl]-7-methylimidazo[1,2-a]pyridine → 2-[4-[4-Hydroxybutyl]phenyl]-7-methylimidazo[1,2-a]pyridine

https://huagongshe.com/reaction/1824548

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-[4-[4-Hydroxybut-1-ynyl]phenyl]-7-methylimidazo[1,2-a]pyridineHCID 22015594—
KatalysatorPalladiumHCID 23938—
LösungsmittelEthanolHCID 702—
Produkt2-[4-[4-Hydroxybutyl]phenyl]-7-methylimidazo[1,2-a]pyridineHCID 2201565592,6%

Reaktionsschritte

The product of Step B, Example 33 (0.3 g) in ethanol (15 mL) was hydrogenated over 5% palladium on barium sulfate (0.06 g) for 4.5 hours. The reaction mixture was filtered and evaporated to afford the title compound (0.282 g).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07041828B2
Quelldatensatzuspto-grants-2006_05
ORD IDord-7dabd75f4f5445a89911f985c724bbc0
Quellennotizuspto-grants-2006_05