4-(Trifluoromethyl)benzenesulfonamide → N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-4-trifluoromethyl-benzenesulfonamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-(Trifluoromethyl)benzenesulfonamide	HCID 70018	—
Edukt	3-[4-(Z)-(1,2-diphenylbut-1-enyl)phenyl]-acrylic acid	HCID 3036152	—
Produkt	N-{3-[4-(1,2-diphenyl-but-1-enyl)-phenyl]-acryloyl}-4-trifluoromethyl-benzenesulfonamide	HCID 69780578	—

Reaktionsschritte

Prepared by coupling 1a and 4-(trifluoromethyl)-benzenesulfonamide (Synlett, 1997, 375) in accordance with Procedure 1, Method B described hereinabove. Yield (18%); 1H NMR (d6-DMSO) δ 12.46 (br s, 1H), 8.11 (d, J=8.5 Hz, 2H), 7.99 (d, J=8.5 Hz, 2H), 7.40–7.07 (m, 13H), 6.84 (d, J=8.1 Hz, 2H), 6.40 (d, J=15.7 Hz, 1H), 2.35 (q, J=7.3 Hz, 2H), 0.81 (t, J=7.3 Hz, 3H); APcI m/z: 562 (M+H+).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07045540B2
Quelldatensatz	uspto-grants-2006_05
ORD ID	ord-1845eabeb0334af383295056a1f54fd4
Quellennotiz	uspto-grants-2006_05