HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(6-fluoro-1H-indol-3-yl)ethanamine → 2-Methyl-6-(thieno[3,2-b]pyridin-7-yloxy)-benzofuran-3-carboxylic acid [2-(6-fluoro-1H-indol-3-yl)-ethyl]-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(6-fluoro-1H-indol-3-yl)ethanamine | HCID 854024 | — |
| Edukt | 2-Methyl-6-[thieno[3,2-b]pyridin-7-yloxy]benzofuran-3-carboxylic acid | HCID 22143510 | — |
| Produkt | 2-Methyl-6-(thieno[3,2-b]pyridin-7-yloxy)-benzofuran-3-carboxylic acid [2-(6-fluoro-1H-indol-3-yl)-ethyl]-amide | HCID 20767889 | — |
Reaktionsschritte
This material was prepared from 2-methyl-6-[thieno[3,2-b]pyridin-7-yloxy]benzofuran-3-carboxylic acid 100 and 2-(6-fluoro-1H-indol-3-yl)ethylamine in a similar manner as that described for example 102. 1H NMR (CD3CN) δ 8.48 (1H, d, J=5.6 Hz), 7.91 (1H, d, J=5.6 Hz), 7.63–7.59 (2H, m), 7.54 (1H, d, J=5.6 Hz), 7.38 (1H, d, J=2.3 Hz), 7.17 (1H, d, J=2.3 Hz), 7.14 (1H, t, J=2.3 Hz), 7.11 (1H, d, J=2.3 Hz), 6.85 (1H, m), 6.65 (1H, bm), 6.61 (1H, d, J=5.6 Hz), 3.69 (2H, q, J=7.1 Hz), 3.06 (2H, t, J=7.1 Hz), 2.57 (3H, s).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07045528B2 |
| Quelldatensatz | uspto-grants-2006_05 |
| ORD ID | ord-1209fcaa5f994665a4b0f8f116c19a6c |
| Quellennotiz | uspto-grants-2006_05 |