[OH:1][C:2]1[C:3]([N+:9]([O-:11])=[O:10])=[N:4][CH:5]=[CH:6][C:7]=1[CH3:8].[C:12](=O)([O-])[O-].[Cs+].[Cs+].CI.C(OCC)(=O)C>CN(C)C=O.CCCCCC>[CH3:12][O:1][C:2]1[C:3]([N+:9]([O-:11])=[O:10])=[N:4][CH:5]=[CH:6][C:7]=1[CH3:8]3-Hydroxy-4-methyl-2-nitropyridine (5 g) was dissolved in dimethylformamide (50 ml), added with cesium carbonate (11.6 g) and methyl iodide (13.7 g), and then the mixture was stirred overnight at room temperature. The reaction mixture was added with ethyl acetate and hexane, washed with water and dried over magnesium sulfate, and then the solvent was evaporated under reduced pressure to obtain the title compound (quantitative).
Wird geladen…
