HCID 22049712, Verbindung → HCID 22049746, Verbindung
Reaktionsgleichung
Br[CH2:2][C:3]([C:5]1[CH:6]=[N:7][CH:8]=[CH:9][C:10]=1[CH3:11])=O.[CH3:12][O:13][C:14]1[N:19]=[C:18]([O:20][CH3:21])[C:17]([C:22](=[S:24])[NH2:23])=[CH:16][N:15]=1>>[CH3:12][O:13][C:14]1[N:19]=[C:18]([O:20][CH3:21])[C:17]([C:22]2[S:24][CH:2]=[C:3]([C:5]3[CH:6]=[N:7][CH:8]=[CH:9][C:10]=3[CH3:11])[N:23]=2)=[CH:16][N:15]=1Komponenten
3
Versuchsvorschrift
By the reaction in the same manner as in Example 25-ii) using 2,4-dimethoxy-5-pyrimidinecarbonitrile (1.32 g), crude 2,4-dimethoxypyrimidine-5-carbothioamide (1.92 g) was obtained as a brown powder. Then, by the reaction in the same manner as in Example 25-iii) using 2-bromo-1-(4-methylpyridin-3-yl)ethanone hydrobromate (1.07 g) and 2,4-dimethoxypyrimidine-5-carbothioamide (880 mg), the title compound (235 mg) was obtained as colorless powder crystals.
Aufarbeitung
- customThen, by the reaction in the same manner as in Example 25-iii)