4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol → 3-Methyl-piperidine-1-carboxylic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl ester

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol	HCID 155241	—
Edukt	3-methyl-1-(3-methylpiperidine-1-carbonyl)-1H-imidazol-3-ium iodide	HCID 43145417	—
Produkt	3-Methyl-piperidine-1-carboxylic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl ester	HCID 23635634	—

Reaktionsschritte

The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenol and 1-methyl-3-(3-methyl-piperidine-1-carbonyl)-3H-imidazol-1-ium iodide. The crude product was purified by flash chromatography using a Quad flash 25 (ethyl acetate/heptane (1:6), (75%, white crystals). HPLC-MS m/z=381.1 (M+1), Rt: 5.4 min.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07067517B2
Quelldatensatz	uspto-grants-2006_06
ORD ID	ord-de11d8660a334c8abb413d52aff7a5f6
Quellennotiz	uspto-grants-2006_06