Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic Acid 4-morpholin-4-yl-phenyl Ester

HRID 1831198

Reaktionsgleichung

Reaktionsgleichung von HRID 1831198
[N:1]1([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH3:14][N:15]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:16](Cl)=[O:17]>>[N:1]1([C:7]2[CH:8]=[CH:9][C:10]([O:13][C:16](=[O:17])[N:15]([CH3:14])[C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:11][CH:12]=2)[CH2:2][CH2:3][O:4][CH2:5][CH2:6]1

Komponenten

3

Edukt 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 805104-Morpholinophenol

Produkt 1

HCID 10171887Methyl-phenyl-carbamic Acid 4-morpholin-4-yl-phenyl Ester

Versuchsvorschrift

The title product was prepared from and 4-morpholin-4-yl-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was extracted with dichloromethane from citric acid (5%). The combined organic phases were evaporated and the product crystallized from ethanol (22%, crystals). HPLC-MS: m/z=313.2 (M+1); Rt: 3.75 min.

Aufarbeitung

  1. extractionThe crude product was extracted with dichloromethane from citric acid (5%)
  2. customThe combined organic phases were evaporated
  3. customthe product crystallized from ethanol (22%, crystals)

Quellen und Nachweise

ORD-Eintrag
ord-5a6d8a4f28b2475a895bfa75388b7a92
Quelldatensatz
uspto-grants-2006_06
Patentnummer
US07067517B2

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