Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic Acid 4-morpholin-4-yl-phenyl Ester
Reaktionsgleichung
[N:1]1([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH3:14][N:15]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:16](Cl)=[O:17]>>[N:1]1([C:7]2[CH:8]=[CH:9][C:10]([O:13][C:16](=[O:17])[N:15]([CH3:14])[C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:11][CH:12]=2)[CH2:2][CH2:3][O:4][CH2:5][CH2:6]1Komponenten
3
Versuchsvorschrift
The title product was prepared from and 4-morpholin-4-yl-phenol and N-methyl-N-phenylcarbamoyl chloride. The crude product was extracted with dichloromethane from citric acid (5%). The combined organic phases were evaporated and the product crystallized from ethanol (22%, crystals). HPLC-MS: m/z=313.2 (M+1); Rt: 3.75 min.
Aufarbeitung
- extractionThe crude product was extracted with dichloromethane from citric acid (5%)
- customThe combined organic phases were evaporated
- customthe product crystallized from ethanol (22%, crystals)