N-acetyl-N-methylcarbamoyl chloride → 2-[O-(N-acetyl-N-methylcarbamoyl)oximino]-3,3-dimethyltetrahydro-1,4-thiazin-5-one
Reaktionsgleichung
[C:1]([N:4]([CH3:8])[C:5](Cl)=[O:6])(=[O:3])[CH3:2].[N:9](=[C:11]1[C:16]([CH3:18])([CH3:17])[NH:15][C:14](=[O:19])[CH2:13][S:12]1)[OH:10]>>[C:1]([N:4]([CH3:8])[C:5]([O:10][N:9]=[C:11]1[C:16]([CH3:17])([CH3:18])[NH:15][C:14](=[O:19])[CH2:13][S:12]1)=[O:6])(=[O:3])[CH3:2]Komponenten
3
Versuchsvorschrift
Utilizing the procedure of Example XII, N-acetyl-N-methylcarbamic acid chloride was reacted with 2-oximino-3,3-dimethyltetrahydro-1,4-thiazin-5-one to yield 2-[O-(N-acetyl-N-methylcarbamoyl)oximino]-3,3-dimethyltetrahydro-1,4-thiazin-5-one, m.p. 218°-220° C. The nmr spectrum supported the proposed structure.
Quellen und Nachweise
- ORD-Eintrag
- ord-d0bad5f80a55435f9a8da9045017a31d
- Quelldatensatz
- uspto-grants-1978_01
- DOI