19-Hydroxy-4-methyl-4,6-androstadiene-3,17-dione → 4-Methyl-4,6-androstadiene-3,17,19-trione
Reaktionsgleichung
[OH:1][CH2:2][C@@:3]12[C@@H:20]3[C@H:11]([C@H:12]4[C@@:16]([CH2:18][CH2:19]3)([CH3:17])[C:15](=[O:21])[CH2:14][CH2:13]4)[CH:10]=[CH:9][C:8]1=[C:7]([CH3:22])[C:6](=[O:23])[CH2:5][CH2:4]2.OC[C@@]12[C@@H]3[C@H]([C@H]4[C@@](CC3)(C)C(=O)CC4)C=CC1=CC(=O)CC2>>[CH3:22][C:7]1[C:6](=[O:23])[CH2:5][CH2:4][C@@:3]2([CH:2]=[O:1])[C:8]=1[CH:9]=[CH:10][C@@H:11]1[C@@H:20]2[CH2:19][CH2:18][C@@:16]2([CH3:17])[C@H:12]1[CH2:13][CH2:14][C:15]2=[O:21]Komponenten
3
Versuchsvorschrift
Substituting 19-hydroxy-4-methyl-4,6-androstadiene-3,17-dione for the 19-hydroxy-4,6-androstadiene-3,17-dione above results in the preparation of 4-methyl-4,6-androstadiene-3,17,19-trione.
Quellen und Nachweise
- ORD-Eintrag
- ord-18288b612c53493e816df635a4a7c0b1
- Quelldatensatz
- uspto-grants-1978_01