Hydrochloric Acid → HCID 22678561, Verbindung

HRID 1837688Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1837688
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][CH2:15][C:16]2[S:17][CH:18]=[CH:19][C:20]=2[S:21]([CH3:24])(=[O:23])=[O:22])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:25]>C(OCC)(=O)C>[ClH:25].[CH3:24][S:21]([C:20]1[CH:19]=[CH:18][S:17][C:16]=1[CH2:15][CH2:14][CH:11]1[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1)(=[O:22])=[O:23]

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 226783201-Tert-butoxycarbonyl-4-[2-(3-methylsulfonyl-2-thienyl)ethyl]piperidine

Produkt 1

HCID 22678561HCID 22678561, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8857Ethyl AcetateLösungsmittel2×

Versuchsvorschrift

11.1 g of 1-tert-butoxycarbonyl-4-[2-(3-methylsulfonyl-2-thienyl)ethyl]piperidine was dissolved in 100 ml of ethyl acetate, 100 ml of an ethyl acetate solution of 4N hydrochloric acid was added thereto, and the mixture was further stirred at room temperature for 2 hours. The resulting crystals were collected by filtration, washed with ethyl acetate, and air-dried, to give 7.92 g of the title compound as colorless crystals.

Aufarbeitung

  1. filtrationThe resulting crystals were collected by filtration
  2. washwashed with ethyl acetate
  3. customair-dried

Quellen und Nachweise

ORD-Eintrag
ord-e6d41132ce9540478b98fcd511322d1d
Quelldatensatz
uspto-grants-2004_08
Patentnummer
US06784192B2

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